For me, despair is not a goal, or a set of principles, or a lifestyle, or even an instinct... It's what defines me as Junko Enoshima! It's just my characterization! That's why I'm able to pursue despair with such purity!
Hope is harmony. A just heart, moving toward the light. That is all. Despair is hope's polar opposite. It is messy and confusing. Despair swallows up love, hatred, and everything else. Because not knowing where you will end up is despair. Despair is what even you cannot predict. Only despair's unpredictability will save you from a boring future.